For those who may wish to understand my and my collaborator's work on the structure and function of G protein-coupled receptors, I’ve provided the following links to the papers that are most important for understanding this work. I like to bunch them into groups of three. First are:
Weber's Law Modeled by the Mathematical Description of a Beam Balance, Mathematical Biosciences 122: 89-94 (1994)
Method for determining drug compositions to prevent desensitization of cellular receptors, US Patent # 5,597,699 (1997)
Activation of G Protein-Coupled Receptors Entails Cysteine Modulation of Agonist Binding, J. Molecular Structure (Theochem), 430/1-3: 57-71 (1998)
The next three papers are:
Compositions to enhance the safety and efficacy of bio-pharmaceutical drugs. US Patent# 6,593,094 (2003)
Optimal Agonist/Antagonist Combinations Maintain Receptor Response by Preventing Rapid Beta-1 adrenergic Receptor Desensitization Intl. J. Pharmacol., 1(2): 122-131, (2005)
Molecular dynamics of a biophysical model for beta-2-adrenergic and G protein-coupled receptor activation Journal of Molecular Graphics and Modelling 25: 396-409 (2006)
1 comment:
Hello,
Thank you very much for your ideas to post comments. G-protein coupled receptors is to transmit signals into the cell. These receptors activate G proteins, which proteins respond to a wide range of agonists, including photon, amines, hormones, neurotransmitters and proteins...
Post a Comment